Complement C5 Convertase, Classical Pathway

**Definition:** A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.

**Tree numbers:** - D12.776.124.486.274.045.387.750.750

**Synonyms:** - Classical Pathway C5 Convertase - C5 Convertase (C4b2a3b) - Classical C5 Convertase