Protein Kinase C-epsilon

**Definition:** A protein kinase C subtype that was originally characterized as a CALCIUM-independent, serine-threonine kinase that is activated by PHORBOL ESTERS and DIACYLGLYCEROLS. It is targeted to specific cellular compartments in response to extracellular signals that activate G-PROTEIN-COUPLED RECEPTORS; TYROSINE KINASE RECEPTORS; and intracellular protein tyrosine kinase.

**Tree numbers:** - D08.811.913.696.620.682.700.725.750 - D12.776.476.563.725.750

**Synonyms:** - PKC epsilon - Protein Kinase C epsilon - PKC-epsilon Serine Threonine Kinase