Proglucagon

**Definition:** The common precursor polypeptide of pancreatic GLUCAGON and intestinal GLUCAGON-LIKE PEPTIDES. Proglucagon is the 158-amino acid segment of preproglucagon without the N-terminal signal sequence. Proglucagon is expressed in the PANCREAS; INTESTINES; and the CENTRAL NERVOUS SYSTEM. Posttranslational processing of proglucagon is tissue-specific yielding numerous bioactive peptides.

**Tree numbers:** - D06.472.317.680 - D06.472.699.587.730 - D12.644.548.586.730 - D12.776.811.700

**Synonyms:** - Pro-Glucagon