Fas Ligand Protein

**Definition:** A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.

**Tree numbers:** - D09.400.430.890.312 - D12.644.276.374.750.249 - D12.776.395.550.312 - D12.776.467.374.750.249 - D12.776.543.550.312 - D23.529.374.750.249

**Synonyms:** - Tumor Necrosis Factor Ligand Superfamily Member 6 - CD178 Antigens - CD95 Antigen Ligand - CD95L - Fas Ligand (FasL) - FasL Protein - TNF Superfamily, Member 6 - CD95 Ligand - CD178 Antigen - Fas Ligand - Antigens, CD178