Receptors, Tumor Necrosis Factor, Member 14

**Definition:** A novel member of the tumor-necrosis factor receptor family that can also mediate HERPES SIMPLEX VIRUS TYPE 1 entry into cells. It has specificity for TUMOR NECROSIS FACTOR LIGAND SUPERFAMILY MEMBER 14 and the homotrimeric form of LYMPHOTOXIN-ALPHA. The receptor is abundantly expressed on T-LYMPHOCYTES and may play a role in regulating lymphocyte activation. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

**Tree numbers:** - D12.776.543.750.705.852.760.500 - D12.776.543.750.830.850

**Synonyms:** - HVEM Protein - HveA Protein - Herpesvirus Entry Mediator - Tumor Necrosis Factor Receptor Subfamily, Member 14 - Tumor Necrosis Factor Receptor Superfamily, Member 14