Receptor Activator of Nuclear Factor-kappa B

**Definition:** A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.

**Tree numbers:** - D12.776.543.750.705.852.760.345

**Synonyms:** - Receptor Activator of NF-kappa B - TRANCE-R - TRANCE Receptor - RANK Protein - Receptor Activator of NF-kappaB - TNFRSF11A Protein - Receptors, Tumor Necrosis Factor, Member 11a - Receptor Activator of Nuclear Factor-kappaB - Tumor Necrosis Factor Receptor Superfamily, Member 11a - NF-Kappa B Receptor Activator - CD265 Antigen - NF-KappaB Receptor Activator