Apolipoprotein C-I

**Definition:** A 6.6-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS; INTERMEDIATE-DENSITY LIPOPROTEINS; and HIGH-DENSITY LIPOPROTEINS. Apo C-I displaces APO E from lipoproteins, modulate their binding to receptors (RECEPTORS, LDL), and thereby decrease their clearance from plasma. Elevated Apo C-I levels are associated with HYPERLIPOPROTEINEMIA and ATHEROSCLEROSIS.

**Tree numbers:** - D10.532.091.400.500 - D12.776.070.400.400.500 - D12.776.521.120.400.500

**Synonyms:** - Apo C-I - Apolipoprotein C1