Apolipoprotein C-II

**Definition:** A 9-kDa protein component of VERY-LOW-DENSITY LIPOPROTEINS. It contains a cofactor for LIPOPROTEIN LIPASE and activates several triacylglycerol lipases. The association of Apo C-II with plasma CHYLOMICRONS; VLDL, and HIGH-DENSITY LIPOPROTEINS is reversible and changes rapidly as a function of triglyceride metabolism. Clinically, Apo C-II deficiency is similar to lipoprotein lipase deficiency (HYPERLIPOPROTEINEMIA TYPE I) and is therefore called hyperlipoproteinemia type IB.

**Tree numbers:** - D10.532.091.400.750 - D12.776.070.400.400.750 - D12.776.521.120.400.750

**Synonyms:** - Apo C-II - ApoC2 - Apolipoprotein C-2 - Apolipoprotein CII - Apoprotein C-II