Hyper-IgM Immunodeficiency Syndrome, Type 1

**Definition:** An X-linked hyper-IgM immunodeficiency subtype resulting from mutation in the gene encoding CD40 LIGAND.

**Tree numbers:** - C15.378.147.333.249.500 - C16.320.322.237 - C16.320.798.625.500 - C20.673.430.250.500 - C20.673.795.625.500

**Synonyms:** - HIGM1 Syndrome - Hyper-IgM Syndrome 1 - Hyper-IgM Immunodeficiency, X-Linked - Immunodeficiency with Hyper-IgM, Type 1 - X-Linked Hyper IgM Syndrome - HIGM1