TNF Receptor-Associated Factor 4

**Definition:** A widely expressed member of the TNF receptor-associated family that may play a role in neuronal development and EMBRYOGENESIS. Although TNF receptor-associated factor 4 does not strongly associate with TUMOR NECROSIS FACTOR RECEPTORS it may be a signaling partner with the GLUCOCORTICOID-INDUCED TNFR-RELATED PROTEIN that plays a role in the activation of JNK MITOGEN-ACTIVATED PROTEIN KINASES and NF-KAPPA B.

**Tree numbers:** - D12.644.360.024.500.906 - D12.776.157.057.500.906 - D12.776.476.024.500.906

**Synonyms:** - TNF Receptor-Associated Protein 4 - TRAF4 - Cysteine-Rich Domain Associated with RING and TRAF Domains Protein 1