Caspase 9

**Definition:** A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

**Tree numbers:** - D08.811.277.656.262.500.126.550.900 - D08.811.277.656.300.200.126.550.900 - D12.776.157.057.006.155 - D12.776.476.024.139.155 - D12.776.476.075.358.155 - D12.776.476.075.405.550.900

**Synonyms:** - ICE-LAP6 Protein - Caspase-9 - Apoptotic Protease Activating Factor 3 - ICE-Like Apoptotic Protease 6