Caspase 12

**Definition:** A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.

**Tree numbers:** - D08.811.277.656.262.500.126.550.920 - D08.811.277.656.300.200.126.550.920 - D12.776.476.075.405.550.920

**Synonyms:** - Caspase-12