Caspase 10

**Definition:** A long pro-domain caspase that contains a death effector domain in its pro-domain region. Activation of this enzyme can occur via the interaction of its N-terminal death effector domain with DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEINS. Caspase 10 plays a role in APOPTOSIS by cleaving and activating EFFECTOR CASPASES. Several isoforms of this protein exist due to multiple alternative splicing of its MESSENGER RNA.

**Tree numbers:** - D08.811.277.656.262.500.126.550.910 - D08.811.277.656.300.200.126.550.910 - D12.776.476.075.405.550.910

**Synonyms:** - Caspase-10