Osteopontin

**Definition:** A negatively-charged extracellular matrix protein that plays a role in the regulation of BONE metabolism and a variety of other biological functions. Cell signaling by osteopontin may occur through a cell adhesion sequence that recognizes INTEGRIN ALPHA-V BETA-3.

**Tree numbers:** - D09.400.430.950.837 - D12.644.276.374.625 - D12.776.395.700.837 - D12.776.467.374.625 - D12.776.860.300.762 - D23.529.374.625

**Synonyms:** - Bone Sialoprotein 1 - Bone Sialoprotein I - Secreted Phosphoprotein 1 - Sialoprotein 1