Epithelial Sodium Channels

**Definition:** Sodium channels found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON; the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. They are AMILORIDE-sensitive and play a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.

**Tree numbers:** - D12.776.157.530.400.875.200 - D12.776.543.550.450.875.200 - D12.776.543.585.400.875.200

**Synonyms:** - ENaC (Epithelial Na+ Channel) - Epithelial Amiloride-Sensitive Sodium Channel - Epithelial Sodium Channel - Epithelial Sodium Ion Channels