Matrix Metalloproteinase 14

**Definition:** A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15.

**Tree numbers:** - D08.811.277.656.300.480.525.300.500 - D08.811.277.656.675.374.525.300.500

**Synonyms:** - Membrane-Type 1 Matrix Metalloproteinase - Membrane-Type Matrix Metalloproteinase 1 - MMP-14 Metalloproteinase - MMP-X1 Protein - MMP14 Metalloproteinase - MT-MMP-1 - MT1-Matrix Metalloproteinase - MT1-MMP