Matrix Metalloproteinase 16

**Definition:** A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the proteolytic action of PROPROTEIN CONVERTASES. Matrix metalloproteinase 16 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of other MATRIX METALLOPROTEINASES such as the zymogen of MATRIX METALLOPROTEINASE 2.

**Tree numbers:** - D08.811.277.656.300.480.525.300.600 - D08.811.277.656.675.374.525.300.750

**Synonyms:** - MMP-16 Metalloproteinase - MMP-X2 Protein - MMP16 Metalloproteinase - MT3-Matrix Metalloproteinase - MT3-MMP - Membrane-Type 3 Matrix Metalloproteinase - Membrane-Type-3 Matrix Metalloproteinase - Membrane-Type Matrix Metalloproteinase 3