Leukokeratosis, Hereditary Mucosal

**Definition:** An autosomal dominant disorder that is manifested by thickened spongiform ORAL MUCOSA with a white opalescent tint. Other MUCOSAL TISSUE may also be involved mucosa found in the VAGINA; RECTUM, and NASAL CAVITY may be similarly involved. This form of LEUKOKERATOSIS can be caused by a mutation in the gene for KERATIN 4 and is not considered a PRENEOPLASTIC CONDITION.

**Tree numbers:** - C16.320.850.542 - C17.800.827.595

**Synonyms:** - White Sponge Nevus of Cannon - Hereditary Mucosal Leukokeratosis