D053557Level 8
Keratin-2
**Definition:** A type II keratin found expressed in the upper spinous layer of epidermal KERATINOCYTES. Mutations in genes that encode keratin-2A have been associated with ICHTHYOSIS BULLOSA OF SIEMENS.
**Tree numbers:** - D05.750.078.593.450.600.200 - D12.776.220.475.450.600.200 - D12.776.860.607.650.200
**Synonyms:** - Cytokeratin-2
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