Interleukin-1 Receptor-Associated Kinases

**Definition:** A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.

**Tree numbers:** - D08.811.913.696.620.682.700.526 - D12.776.476.563.526

**Synonyms:** - Interleukin-1 Receptor-Associated Kinase - IRAK Kinases - IL-1 Receptor-Associated Kinase