TYK2 Kinase

**Definition:** A Janus kinase subtype that is involved in signaling from a broad variety of CYTOKINE RECEPTORS. The TYK2 kinase is considered the founding member of the janus kinase family and was initially discovered as a signaling partner for the INTERFERON ALPHA-BETA RECEPTOR. The kinase has since been shown to signal from several INTERLEUKIN RECEPTORS.

**Tree numbers:** - D08.811.913.696.620.682.725.124.650 - D12.776.476.568.124.650

**Synonyms:** - Tyrosine Kinase 2 - Non-Receptor Tyrosine-Protein Kinase TYK2