Syndecans

**Definition:** A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.

**Tree numbers:** - D09.400.430.890.847 - D09.400.430.930.350.500 - D12.776.395.550.847 - D12.776.395.650.350.500 - D12.776.543.550.847

**Synonyms:** - Syndecan