Transforming Growth Factor beta2

**Definition:** A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

**Tree numbers:** - D12.644.276.374.687.200 - D12.644.276.954.775.200 - D12.776.467.374.687.200 - D12.776.467.942.775.200 - D23.529.374.687.200 - D23.529.942.775.200

**Synonyms:** - BSC-1 Cell Growth Inhibitor - Glioblastoma-Derived T-Cell Suppressor Factor - Suppressor Factor, T-Cell, Glioblastoma-Derived - Polyergin - TGF-beta2 - TGF-beta-2 - Cartilage-Inducing Factor-B