Granzymes

**Definition:** A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells.

**Tree numbers:** - D08.811.277.656.300.760.397 - D08.811.277.656.959.350.397

**Synonyms:** - Granzyme