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D054409Level 7

Nicotinamide Phosphoribosyltransferase

**Definition:** An enzyme that catalyzes the formation of nicotinamide mononucleotide (NMN) from nicotinamide and 5-phosphoribosyl-1-pyrophosphate, the rate-limiting step in the biosynthesis of the NAD coenzyme. It is also known as a growth factor for early B-LYMPHOCYTES, or an ADIPOKINE with insulin-mimetic effects (visfatin).

**Tree numbers:** - D08.811.913.400.725.575

**Synonyms:** - NAmPRTase - NAMPT Protein - NMN Pyrophosphorylase - Pre-B-Cell Colony-Enhancing Factor - Visfatin

GET/api/v1/systems/mesh/nodes/D054409
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