D054461Level 9
Lim Kinases
**Definition:** Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
**Tree numbers:** - D08.811.913.696.620.682.700.542 - D12.776.476.563.542 - D12.776.512.124
**Synonyms:** - LIM Kinase - LIM-Kinase - LIM Motif-Containing Protein Kinases
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