p21-Activated Kinases

**Definition:** A family of serine-threonine kinases that bind to and are activated by MONOMERIC GTP-BINDING PROTEINS such as RAC GTP-BINDING PROTEINS and CDC42 GTP-BINDING PROTEIN. They are intracellular signaling kinases that play a role the regulation of cytoskeletal organization.

**Tree numbers:** - D08.811.913.696.620.682.700.596 - D12.776.476.563.596

**Synonyms:** - PAK Kinases - p21-Activated Kinase - PAK Kinase