Peroxiredoxins

**Definition:** A family of ubiquitously-expressed peroxidases that play a role in the reduction of a broad spectrum of PEROXIDES like HYDROGEN PEROXIDE; LIPID PEROXIDES and peroxinitrite. They are found in a wide range of organisms, such as BACTERIA; PLANTS; and MAMMALS. The enzyme requires the presence of a thiol-containing intermediate such as THIOREDOXIN as a reducing cofactor.

**Tree numbers:** - D08.811.682.732.850

**Synonyms:** - Alkylhydroperoxide Reductase - Peroxidoxin - Peroxiredoxin - Protector Protein (Mixed-Function Oxidase Systems) - Thiol-Specific Antioxidant Protein - Alkyl Hydroperoxide Reductase - Thioredoxin Peroxidase