Group IV Phospholipases A2

**Definition:** A cytosolic phospholipase A2 group that plays an important role in the release of free ARACHIDONIC ACID, which in turn is metabolized to PROSTAGLANDINS by the CYCLOOXYGENASE pathway and to LEUKOTRIENES by the 5-LIPOXYGENASE pathway.

**Tree numbers:** - D08.811.277.352.100.680.750.937.625.249

**Synonyms:** - Group IV Cytosolic Phospholipase A2 - Phospholipase A2 IV - Phospholipases A2, Group IV - PLA(2)-IV - PLA2-IV