Group III Phospholipases A2

**Definition:** A subcategory of secreted phospholipases A2 with specificity for PHOSPHATIDYLETHANOLAMINES and PHOSPHATIDYLCHOLINE. It occurs as a component of VENOMS and as a mammalian secretory phospholipase A2. The creation of this group is based upon similarities in the structural determinants of the enzymes including a long amino-terminal domain, a conserved group III-specific domain, and a long carboxyl-terminal domain.

**Tree numbers:** - D08.811.277.352.100.680.750.937.750.662

**Synonyms:** - Group III Secretory Phospholipase A2 - Phospholipase A2-III - Phospholipases A2, Group III