Cyclic Nucleotide Phosphodiesterases, Type 5

**Definition:** A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

**Tree numbers:** - D08.811.277.352.640.150.500 - D08.811.277.352.640.155.500 - D12.776.476.008.500 - D12.776.476.009.500

**Synonyms:** - Phosphodiesterase 5A - Phosphodiesterase Type 5 - Phosphodiesterase Type V - Phosphodiesterase 5 - Phosphodiesterase-5 - Phosphodiesterase V - cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase - Phosphodiesterase 5A, cGMP-Specific - PDE5 Phosphodiesterases