PDZ Domains

**Definition:** Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.

**Tree numbers:** - G02.111.570.820.709.275.750.500.500

**Synonyms:** - GLGF Repeats Domains - DHR Domains - PSD95-DLG-ZO1 Domains - DLG Homology Repeats Domains - PDZ Interaction Domains