Elongation Factor 2 Kinase

**Definition:** A monomeric calcium-calmodulin-dependent protein kinase subtype that specifically phosphorylates PEPTIDE ELONGATION FACTOR 2. The enzyme lacks a phosphorylatable activation domain that can respond to CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE, however it is regulated by phosphorylation by PROTEIN KINASE A and through intramolecular autophosphorylation.

**Tree numbers:** - D08.811.913.696.620.682.700.125.425 - D12.776.476.563.125.425

**Synonyms:** - Calmodulin-Dependent Protein Kinase III - Protein Kinase CPK3 - Calcium-Calmodulin-Dependent Protein Kinase Type 3 - Eukaryotic Elongation Factor-2 Kinase - CAM Kinase III - Cam PK III - E-2 Kinase - EF-2 Kinase - eEF-2-Specific Ca and Calmodulin-Dependent Protein Kinase III