A Kinase Anchor Proteins

**Definition:** A structurally-diverse family of intracellular-signaling adaptor proteins that selectively tether specific protein kinase A subtypes to distinct subcellular sites. They play a role in focusing the PROTEIN KINASE A activity toward relevant substrates. Over fifty members of this family exist, most of which bind specifically to regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE II such as CAMP PROTEIN KINASE RIIALPHA or CAMP PROTEIN KINASE RIIBETA.

**Tree numbers:** - D12.644.360.024.065 - D12.776.157.057.003 - D12.776.476.024.069

**Synonyms:** - A-Kinase Anchoring Protein - A-Kinase Anchoring Proteins - A-Kinase Anchor Proteins - Protein Kinase A Anchor Proteins