AMP-Activated Protein Kinases

**Definition:** Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their activity largely depends upon the concentration of cellular AMP which is increased under conditions of low energy or metabolic stress. AMP-activated protein kinases modify enzymes involved in LIPID METABOLISM, which in turn provide substrates needed to convert AMP into ATP.

**Tree numbers:** - D08.811.913.696.620.682.700.085 - D12.776.476.563.085

**Synonyms:** - 5'-AMP-Activated Protein Kinase - AMP-Activated Kinase - AMP-Activated Protein Kinase