Bone Morphogenetic Protein 1

**Definition:** A bone morphogenetic protein family member that includes an active tolloid-like metalloproteinase domain. The metalloproteinase activity of bone morphogenetic protein 1 is specific for the removal of the C-propeptide of PROCOLLAGEN and may act as a regulator of EXTRACELLULAR MATRIX deposition. Alternative splicing of MRNA for bone morphogenetic protein 1 results in the production of several PROTEIN ISOFORMS.

**Tree numbers:** - D08.811.277.656.300.480.525.700.049 - D08.811.277.656.675.374.525.700.900.500 - D12.644.276.954.200.100 - D12.776.467.836.049 - D12.776.467.942.200.100 - D12.776.467.948.500 - D23.529.942.200.100 - D23.529.948.500

**Synonyms:** - Procollagen C-Endopeptidase