Bone Morphogenetic Protein 5

**Definition:** A bone morphogenetic protein that may play a role in CARTILAGE formation. It is a potent regulator of the growth of CHONDROCYTES and the synthesis of cartilage matrix proteins. Evidence for its role in cartilage formation can be seen in MICE, where genetic mutations that cause loss of bone morphogenetic protein 5 function result in the formation of small malformed ears.

**Tree numbers:** - D12.644.276.954.200.500 - D12.776.467.942.200.500 - D23.529.942.200.500

**Synonyms:** - BMP-5