Nodal Signaling Ligands

**Definition:** Members of the transforming growth factor superfamily that play a role in pattern formation and differentiation during the pregastrulation and GASTRULATION stages of chordate development. Several nodal signaling ligands are specifically involved in the genesis of left-right asymmetry during development. The protein group is named after a critical region of the vertebrate embryo PRIMITIVE STREAK referred to as HENSEN'S NODE.

**Tree numbers:** - D12.644.276.954.550 - D12.776.467.942.550 - D23.529.942.550

**Synonyms:** - Nodal Signaling Proteins