Chromatin Assembly Factor-1

**Definition:** A histone chaperone protein that plays a role in the deposition of NUCLEOSOMES on newly synthesized DNA. It is comprised of three different subunits of 48, 60, and 150 kDa molecular size. The 48 kDa subunit, RETINOBLASTOMA-BINDING PROTEIN 4, is also a component of several other protein complexes involved in chromatin remodeling.

**Tree numbers:** - D12.776.580.219.200

**Synonyms:** - Chromatin Assembly Complex-1