Cyclin-Dependent Kinase 8

**Definition:** A CYCLIN C dependent kinase that is an important component of the mediator complex. The enzyme is activated by its interaction with CYCLIN C and plays a role in transcriptional regulation by phosphorylating RNA POLYMERASE II.

**Tree numbers:** - D05.500.374.500 - D08.811.913.696.620.682.700.646.500.968 - D12.776.157.057.072.500 - D12.776.167.200.548 - D12.776.476.024.388.500 - D12.776.476.563.646.500.968 - D12.776.660.551.500

**Synonyms:** - Cell Division Protein Kinase 8 - Cdk8 Cyclin-Dependent Kinase - Cdk8 Protein Kinase