Mediator Complex Subunit 1

**Definition:** A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.

**Tree numbers:** - D05.500.374.750 - D12.644.360.024.309.750 - D12.644.360.024.314.049 - D12.776.157.057.072.750 - D12.776.157.057.080.049 - D12.776.476.024.388.750 - D12.776.476.024.394.049 - D12.776.660.551.750 - D12.776.660.675.049 - D12.776.930.617.049

**Synonyms:** - TRAP220 - Mediator of RNA Polymerase II Transcription Subunit 1 - p53 Regulatory Protein RB18A - RB18A - Thyroid Hormone Receptor Associated Protein 220 - Peroxisome Proliferator-Activated Receptor Binding Protein - PPAR-Binding Protein - Thyroid Receptor Interacting Protein 2 - TR-Associated Protein P220 - TRIP2 (Thyroid Receptor Interacting Protein 2) - DRIP205 - Vitamin D Receptor-Interacting Protein Complex Component DRIP205