World Of Taxonomy
D056921Level 9

Nuclear Receptor Coactivator 3

**Definition:** A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. It contains a histone acetyltransferase activity that may play a role in CHROMATIN REMODELING during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS such as those found in BREAST CANCER.

**Tree numbers:** - D08.811.913.050.134.415.500.150 - D12.644.360.024.314.300 - D12.776.157.057.080.300 - D12.776.476.024.394.300 - D12.776.660.675.300 - D12.776.930.617.300

**Synonyms:** - Nuclear Receptor Coactivator-3 - Receptor-Associated Coactivator 3 - Amplified in Breast Cancer-1 Protein - Steroid Receptor Coactivator 3 - Thyroid Hormone Receptor Activator Molecule 1

GET/api/v1/systems/mesh/nodes/D056921
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