Hyaline Fibromatosis Syndrome

**Definition:** Autosomal recessive disorder characterized by HYALINE deposition in the skin, bone, gastrointestinal tract, muscles and glands; multiple subcutaneous skin nodules; GINGIVAL HYPERTROPHY; and joint CONTRACTURES. Mutations in the capillary morphogenesis protein-2 are associated with the disorder.

**Tree numbers:** - C16.320.850.368 - C17.800.827.384

**Synonyms:** - Puretic Syndrome - Juvenile Hyalinosis - Murray Syndrome - Hyalinosis, Systemic - Systemic Hyalinosis - Juvenile Hyaline Fibromatosis - Fibromatosis Hyalinica Multiplex Juvenilis - Fibromatosis Juvenile Hyaline - Hyaline Fibromatosis Juvenile - Hyalinosis, Systemic Juvenile - Fibromatosis, Juvenile Hyaline