Tetraspanins

**Definition:** A large superfamily of cell surface membrane proteins characterized by their four transmembrane domains. They play a role in a variety of processes such as cellular adhesion and motility. They may be involved in the organization of cell surface MEMBRANE MICRODOMAINS that regulate the activation of LEUKOCYTES.

**Tree numbers:** - D12.776.543.900

**Synonyms:** - Tetraspanin