Endoplasmic Reticulum Stress

**Definition:** Various physiological or molecular disturbances that impair ENDOPLASMIC RETICULUM function. It triggers many responses, including UNFOLDED PROTEIN RESPONSE, which may lead to APOPTOSIS; and AUTOPHAGY.

**Tree numbers:** - G04.434

**Synonyms:** - ER Stress - Stress, Endoplasmic Reticulum