Hand-Foot Syndrome

**Definition:** Chemotherapy-induced dermal side effects that are associated with the use of various CYTOSTATIC AGENTS. Symptoms range from mild ERYTHEMA and/or PARESTHESIA to severe ulcerative dermatitis with debilitating pain involving typically palmoplantar and intertriginous areas. These cutaneous manifestations are sometimes accompanied by nail anomalies.

**Tree numbers:** - C17.800.174.600.587 - C25.100.468.380.587

**Synonyms:** - Chemotherapy-Induced Acral Erythema - Chemotherapy-Induced Palmoplantar Erythrodysesthesia