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D062965Level 11

Cyclic GMP-Dependent Protein Kinase Type I

**Definition:** A cyclic GMP-dependent protein kinase subtype that is expressed in SMOOTH MUSCLE tissues and plays a role in regulation of smooth muscle contraction. Two isoforms, PKGIalpha and PKGIbeta, of the type I protein kinase exist due to alternative splicing of its mRNA.

**Tree numbers:** - D08.811.913.696.620.682.700.150.150.500 - D12.776.476.563.150.150.500

**Synonyms:** - cGMP-Dependent Protein Kinase I

GET/api/v1/systems/mesh/nodes/D062965
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