Sialic Acid Binding Immunoglobulin-like Lectins

**Definition:** A family of SIALIC ACID binding proteins found in vertebrate species. They are transmembrane proteins which act as cell surface receptors for a variety of sialylated GLYCOCONJUGATES. While a subset of siglec protein subtypes are evolutionarily conserved between mammalian species, there are many others that are species specific.

**Tree numbers:** - D12.776.503.921

**Synonyms:** - Siglecs - Sialic Acid Binding Ig-like Lectin - Sialic Acid-binding Hemagglutinin - Siglec