Ataxia Telangiectasia Mutated Proteins

**Definition:** A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

**Tree numbers:** - D08.811.913.696.620.682.700.097 - D12.776.157.687.125 - D12.776.476.563.097 - D12.776.660.720.125

**Synonyms:** - ATM Protein - A-T Protein - AT Mutated Protein