Rho Guanine Nucleotide Exchange Factors

**Definition:** Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.

**Tree numbers:** - D12.644.360.325.300.099 - D12.776.476.325.300.099